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Book I chapter 13
Now the extent of exactitude and truth in the doctrines of Hippocrates may be gauged, not merely from the way in which his opponents are at variance with obvious facts, but also from the various subjects of natural research themselves — the functions of animals, and the rest. For those people who do not believe that there exists in any part of the animal a faculty for attracting its own special quality are compelled repeatedly to deny obvious facts. For instance, Asclepiades, the physician, did this in the case of the kidneys. That these are organs for secreting [separating out] the urine, was the belief not only of Hippocrates, Diocles, Erasistratus, Praxagoras, and all other physicians of eminence, but practically every butcher is aware of this, from the fact that he daily observes both the position of the kidneys and the duct (termed the ureter) which runs from each kidney into the bladder, and from this arrangement he infers their characteristic use and faculty. But, even leaving the butchers aside, all people who suffer either from frequent dysuria or from retention of urine call themselves “nephritics,” when they feel pain in the loins and pass sandy matter in their water.

I do not suppose that Asclepiades ever saw a stone which had been passed by one of these sufferers, or observed that this was preceded by a sharp pain in the region between kidneys and bladder as the stone traversed the ureter, or that, when the stone was passed, both the pain and the retention at once ceased. It is worth while, then, learning how his theory accounts for the presence of urine in the bladder, and one is forced to marvel at the ingenuity of a man who puts aside these broad, clearly visible routes,2 and postulates others which are narrow, invisible — indeed, entirely imperceptible. His view, in fact, is that the fluid which we drink passes into the bladder by being resolved into vapours, and that, when these have been again condensed, it thus regains its previous form, and turns from vapour into fluid. He simply looks upon the bladder as a sponge or a piece of wool, and not as the perfectly compact and impervious body that it is, with two very strong coats. For if we say that the vapours pass through these coats, why should they not pass through the peritoneum and the diaphragm, thus filling the whole abdominal cavity and thorax with water? “But,” says he, “of course the peritoneal coat is more impervious than the bladder, and this is why it keeps out the vapours, while the bladder admits them.” Yet if he had ever practised anatomy, he might have known that the outer coat of the bladder springs from the peritoneum and is essentially the same as it, and that the inner coat, which is peculiar to the bladder, is more than twice as thick as the former.

Perhaps, however, it is not the thickness or thinness of the coats, but the situation of the bladder, which is the reason for the vapours being carried into it? On the contrary, even if it were probable for every other reason that the vapours accumulate there, yet the situation of the bladder would be enough in itself to prevent this. For the bladder is situated below, whereas vapours have a natural tendency to rise upwards; thus they would fill all the region of the thorax and lungs long before they came to the bladder.

But why do I mention the situation of the bladder, peritoneum, and thorax? For surely, when the vapours have passed through the coats of the stomach and intestines, it is in the space between these and the peritoneum that they will collect and become liquefied (just as in dropsical subjects it is in this region that most of the water gathers). Otherwise the vapours must necessarily pass straight forward through everything which in any way comes in contact with them, and will never come to a standstill. But, if this be assumed, then they will traverse not merely the peritoneum but also the epigastrium, and will become dispersed into the surrounding air; otherwise they will certainly collect under the skin.

Even these considerations, however, our present-day Asclepiadeans attempt to answer, despite the fact that they always get soundly laughed at by all who happen to be present at their disputations on these subjects — so difficult an evil to get rid of is this sectarian partizanship, so excessively resistant to all cleansing processes, harder to heal than any itch!

Thus, one of our Sophists who is a thoroughly hardened disputer and as skilful a master of language as there ever was, once got into a discussion with me on this subject; so far from being put out of countenance by any of the above-mentioned considerations, he even expressed his surprise that I should try to overturn obvious facts by ridiculous arguments! “For,” said he, “one may clearly observe any day in the case of any bladder, that, if one fills it with water or air and then ties up its neck and squeezes it all round, it does not let anything out at any point, but accurately retains all its contents. And surely,” said he, “if there were any large and perceptible channels coming into it from the kidneys the liquid would run out through these when the bladder was squeezed, in the same way that it entered?” Having abruptly made these and similar remarks in precise and clear tones, he concluded by jumping up and departing — leaving me as though I were quite incapable of finding any plausible answer!

The fact is that those who are enslaved to their sects are not merely devoid of all sound knowledge, but they will not even stop to learn! Instead of listening, as they ought, to the reason why liquid can enter the bladder through the ureters, but is unable to go back again the same way — instead of admiring Nature’s artistic skill — they refuse to learn; they even go so far as to scoff, and maintain that the kidneys, as well as many other things, have been made by Nature for no purpose! And some of them who had allowed themselves to be shown the ureters coming from the kidneys and becoming implanted in the bladder, even had the audacity to say that these also existed for no purpose; and others said that they were spermatic ducts, and that this was why they were inserted into the neck of the bladder and not into its cavity. When, therefore, we had demonstrated to them the real spermatic ducts entering the neck of the bladder lower down than the ureters, we supposed that, if we had not done so before, we would now at least draw them away from their false assumptions, and convert them forthwith to the opposite view. But even this they presumed to dispute, and said that it was not to be wondered at that the semen should remain longer in these latter ducts, these being more constricted, and that it should flow quickly down the ducts which came from the kidneys, seeing that these were well dilated. We were, therefore, further compelled to show them in a still living animal, the urine plainly running out through the ureters into the bladder; even thus we hardly hoped to check their nonsensical talk.

Now the method of demonstration is as follows. One has to divide the peritoneum in front of the ureters, then secure these with ligatures, and next, having bandaged up the animal, let him go (for he will not continue to urinate). After this one loosens the external bandages and shows the bladder empty and the ureters quite full and distended — in fact almost on the point of rupturing; on removing the ligature from them, one then plainly sees the bladder becoming filled with urine.

When this has been made quite clear, then, before the animal urinates, one has to tie a ligature round his penis and then to squeeze the bladder all over; still nothing goes back through the ureters to the kidneys. Here, then, it becomes obvious that not only in a dead animal, but in one which is still living, the ureters are prevented from receiving back the urine from the bladder. These observations having been made, one now loosens the ligature from the animal’s penis and allows him to urinate, then again ligatures one of the ureters and leaves the other to discharge into the bladder. Allowing, then, some time to elapse, one now demons............
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