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Chapter 10

11 AM

"VIRUSES kill thousands of people every day," Stanley Oxenford said. "About every ten years, an epidemic of influenza kills around twenty-five thousand people in the United Kingdom. In 1918, flu caused more deaths than the whole of World War One. In the year 2002, three million people died of AIDS, which is caused by human immunodeficiency virus. And viruses are involved in ten percent of cancers."

Toni listened intently, sitting beside him in the Great Hall, under the varnished timbers of the mock-medieval roof. He sounded calm and controlled, but she knew him well enough to recognize the barely audible tremor of strain in his voice. He had been shocked and dismayed by Laurence Mahoney's threat, and the fear that he might lose everything was only just concealed by his unruffled facade.

She watched the faces of the assembled reporters. Would they hear what he was saying and understand the importance of his work? She knew journalists. Some were intelligent, many stupid. A few believed in telling the truth; the majority just wrote the most sensational story they could get away with. She felt indignant that they could hold in their hands the fate of a man such as Stanley. Yet the power of the tabloids was a brutal fact of modern life. If enough of these hacks chose to portray Stanley as a mad scientist in a Frankenstein castle, the Americans might be sufficiently embarrassed to pull the finance.

That would be a tragedy—not just for Stanley, but for the world. True, someone else could finish the testing program for the antiviral drug, but a ruined and bankrupt Stanley would invent no more miracle cures. Toni thought angrily that she would like to slap the dumb faces of the journalists and say, "Wake up—this is about your future, too!"

"Viruses are a fact of life, but we don't have to accept that fact passively," Stanley went on. Toni admired the way he spoke. His voice was measured but relaxed. He used this tone when explaining things to younger colleagues. His speech sounded more like a conversation. "Scientists can defeat viruses. Before AIDS, the great killer was smallpox—until a scientist called Edward Jenner invented vaccination in 1796. Now smallpox has disappeared from human society. Similarly, polio has been eliminated in large areas of our world. In time, we will defeat influenza, and AIDS, and even cancer—and it will be done by scientists like us, working in laboratories such as this."

A woman put up a hand and called out. "What are you working on here—exactly?"

Toni said, "Would you mind identifying yourself?"

"Edie McAllan, science correspondent, Scotland on Sunday."

Cynthia Creighton, sitting on the other side of Stanley, made a note.

Stanley said, "We have developed an antiviral drug. That's rare. There are plenty of antibiotic drugs, which kill bacteria, but few that attack viruses."

A man said, "What's the difference?" He added, "Clive Brown, Daily Record."

The Record was a tabloid. Toni was pleased with the direction the questions were taking. She wanted the press to concentrate on real science. The more they understood, the less likely they were to print damaging rubbish.

Stanley said, "Bacteria, or germs, are tiny creatures that can be seen with a normal microscope. Each of us is host to billions of them. Many arc useful, helping us digest food, for example, or dispose of dead skin cells. A few cause illness, and some of those can be treated with antibiotics. Viruses are smaller and simpler than bacteria. You need an electron microscope to see them. A virus cannot reproduce itself— instead, it hijacks the biochemical machinery of a living cell and forces the cell to produce copies of the virus. No known virus is useful to humans. And we have few medicines to combat them. That's why a new antiviral drug is such good news for the human race."

Edie McAllan asked, "What particular viruses is your drug effective against?"

It was another scientific question. Toni began to believe that this press conference would do all that she and Stanley hoped. She quelled her optimism with an effort. She knew, from her experience as a police press officer, that a journalist could ask serious and intelligent questions then go back to the office and write inflammatory garbage. Even if the writer turned in a sensible piece, it might be rewritten by someone ignorant and irresponsible.

Stanley replied, "That's the question we're trying to answer. We're testing the drug against a variety of viruses to determine its range."

Clive Brown said, "Does that include dangerous viruses?"

Stanley said, "Yes. No one is interested in drugs for safe viruses."

The audience laughed. It was a witty answer to a stupid question. But Brown looked annoyed, and Toni's heart sank. A humiliated journalist would stop at nothing to get revenge.

She intervened quickly. "Thank you for that question, Clive," she said, trying to mollify him. "Here at Oxenford Medical we impose the highest possible standards of security in laboratories where special materials are used. In BSL4, which stands for BioSafety Level Four, the alarm system is directly connected with regional police headquarters at Inverburn. There are security guards on duty twenty-four hours a day, and this morning I have doubled the number of guards. As a further precaution, security guards cannot enter BSL4, but monitor the laboratory via closed-circuit television cameras."

Brown was not appeased. "If you've got perfect security, how did the hamster get out?"

Toni was ready for this. "Let me make three points. One, it was not a hamster. You've got that from the police, and it's wrong." She had deliberately given Frank dud information, and he had fallen into her trap, betraying himself as the source of the leaked story. "Please rely on us for the facts about what goes on here. It was a rabbit, and it was not called Fluffy."

They laughed at this, and even Brown smiled.

"Two, the rabbit was smuggled out of the laboratory in a bag, and we have today instituted a compulsory bag search at the entrance to BSL4, to make sure this cannot happen again. Three, I didn't say we had perfect security. I said we set the highest possible standards. That's all human beings can do."

"So you're admitting your laboratory is a danger to innocent members of the Scottish public."

"No. You're safer here than you would be driving on the M8 or taking a flight from Prestwick. Viruses kill many people every day, but only one person has ever died of a virus from our lab, and he was not an innocent member of the public—he was an employee who deliberately broke the rules and knowingly put himself at risk."

On balance it was going well, Toni thought as she looked around for the next question. The television cameras were rolling, the flashguns were popping, and Stanley was coming across as what he was, a brilliant scientist with a strong sense of responsibility. But she was afraid the TV news would throw away the undramatic footage of the press conference in favor of the crowd of youngsters at the gate chanting slogans about animal rights. She wished she could think of something more interesting for the cameramen to point their lenses at.

Frank's friend Carl Osborne spoke up for the first time. He was a good-looking man of about Toni's age with movie-star features. His hair was a shade too yellow to be natural. "Exactly what danger did this rabbit pose to the general public?"

Stanley answered: "The virus is not very infectious across species. In order to infect Michael, we think the rabbit must have bitten him."

"What if the rabbit had got loose?"

Stanley looked out of the window. A light snow was falling. "It would have frozen to death."

"Suppose it had been eaten by another animal. Could a fox have become infected?"

"No. Viruses are adapted to a small number of species, usually one, sometimes two or three. This one does not infect foxes, or any other form of Scottish wildlife, as far as we know. Just humans, macaque monkeys, and certain types of rabbit."

"But Michael could have given the virus to other people."

"By sneezing, yes. This was the possibility that alarmed us most. However, Michael seems not to have seen anyone during the critical period. We have already contacted his colleagues and friends. Nonetheless, we would be grateful if you would use your newspapers and television programs to appeal for anyone who did see him to call us immediately."

"We aren't trying to minimize this," Toni put in hastily. "We are deeply concerned about the incident and, as I've explained, we have already put in stronger security measures. But at the same time we must be careful not to exaggerate." Telling journalists not to exaggerate was a bit like telling lawyers not to be quarrelsome, she thought wryly. "The truth is that the public have not been endangered."

Osborne was not finished. "Suppose Michael Ross had given it to a friend, who had given it to someone else . . . how many people might have died?"

Toni said quickly, "We can't enter into that kind of wild speculation. The virus did not spread. One person died. That's one too many, but it's no reason to start talking about the Four Horsemen of the Apocalypse." She bit her tongue. That was a stupid phrase to use: someone would probably quote it, out of context, and make it seem as if she had been forecasting doomsday.

Osborne said, "I understand your work is financed by the American army."

"The Department of Defense, yes," Stanley said. "They are naturally interested in ways of combating biological warfare."

"Isn't it true that the Americans have this work done in Scotland because they think it's too dangerous to be done in the United States?"

"On the contrary. A great deal of work of this type goes on in the States, at the Centers for Disease Control in Atlanta, Georgia, and at the U.S. Army Medical Research Institute of Infectious Diseases at Fort Detrick."

"So why was Scotland chosen?"

"Because the drug was invented here at Oxenford Medical."

Toni decided to quit while she was ahead and close the press conference. "I don't want to cut t............

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